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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6835 | Fenoldopam mesylate | Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526 | Dopamine Receptor |
Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation. | |||
T7942 | Tranylcypromine hemisulfate | Tranylcypromine Sulfate,Tranylcypromine (hemisulfate) | Histone Demethylase , MAO , Monoamine Oxidase |
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity. | |||
T4418 | GSK2879552 2HCl (1401966-69-5(free base)) | Histone Demethylase | |
GSK2879552 is an orally available, irreversible inhibitor of lysine specific demethylase 1 (LSD1), with potential antineoplastic activity. | |||
T21652 | RN-1 dihydrochloride | Histone Demethylase , MAO | |
RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM). | |||
T83966 | LSD1-IN-30 | Histone Demethylase | |
LSD1-IN-30 is a lysine-specific demethylase 1 (LSD1) inhibitor with anticancer activity for the study of small cell lung cancer and acute myeloid leukemia. | |||
T11882 | Pulrodemstat benzenesulfonate | LSD1-IN-7 benzenesulfonate,CC-90011 benzenesulfonate | Histone Demethylase |
Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity. | |||
T4477 | Domatinostat tosylate | 4SC-202 tosylate,4SC-202 | Apoptosis , HDAC |
Domatinostat tosylate (4SC-202) is a selective inhibitor of class I HDAC for HDAC1/2/3 (IC50: 1.20/1.12/0.57 μM). It also displays inhibitory activity against Lysine-specific demethylase 1 (LSD1). | |||
T6362 | Domatinostat | 4SC202,4SC 202,4SC-202 (free base),4SC-202 | Apoptosis , HDAC |
Domatinostat (4SC202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. Also displays inhibitory activity against Lysine specific demethylase 1 (L... | |||
T39252L | 5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride | Others | |
5-[(1S,2S)-2-[(Cyclopropylmethyl)amino]cyclopropyl]-N-(tetrahydro-2H-pyran-4-yl)thiophene-3-carboxamide hydrochloride is a cyclopropanoid enzyme compound that acts as a lysine-specific demethylase-1 inhibitor for schizop... | |||
T13057 | T-448 | Histone Demethylase | |
T-448 is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM). | |||
T13056 | T-448 free base | Histone Demethylase | |
T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM). | |||
T11883 | Pulrodemstat Methylbenzenesulfonate | LSD1-IN-7 Methylbenzenesulfonate | Others |
LSD1-IN-7 Methylbenzenesulfonate is a potent and orally active inhibitor of lysine specific demethylase-1 (LSD1) with anticancer activity. | |||
T13052 | S2101 | S 2101 | Histone Demethylase |
S 2101 is an inhibitor of lysine-specific demethylase 1 (LSD1)(IC50 of 0.99 μM, Ki of 0.61 μM and Kinact/Ki of 4560 M/s). | |||
T11880 | LSD1-IN-5 | Histone Demethylase | |
LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-5 is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. | |||
T39226 | INCB059872 | INCB059872 | |
INCB059872 is a highly potent, orally active, selective, and irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1). Its chemical properties make it suitable for use in researching myeloid leukemia. | |||
T11881 | LSD1-IN-6 | Histone Demethylase | |
LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1. LSD1-IN-6 is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. | |||
T40420 | Namoline | ||
Namoline is a γ-pyrone compound that functions as a selective and reversible inhibitor of Lysine-specific demethylase 1 (LSD1) with an IC50 of 51 μM in an HRP-coupled enzymatic assay. By impairing LSD1 demethylase activi... | |||
T61565 | KDM5B-IN-3 | ||
KDM5B-IN-3 (Compound 5) is an inhibitor of histone lysine-specific demethylase 5B (KDM5B) or JARID1B. It effectively inhibits the activity of KDM5B with an IC50 value of 9.32 μM. Consequently, KDM5B-IN-3 serves as a valu... | |||
T36625 | LSD1/HDAC6-IN-1 | LSD1/HDAC6-IN-1 | |
LSD1/HDAC6-IN-1 is an orally active compound that functions as a dual inhibitor, targeting lysine specific demethylase 1 (LSD1) and histone deacetylase 6 (HDAC6). This compound demonstrates promising anti-tumor activity ... | |||
T11503 | GSK 690 Hydrochloride | Histone Demethylase | |
GSK 690 (Hydrochloride) is a reversible lysine specific demethylase 1 (LSD1) inhibitor with a Kd value of 9 nM and IC 50 of 37 nM. |